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Of those targets that were identified, PAGln was observed to be significantly elevated ( p = 0.009) in the HD ( n = 126) in comparison to healthy controls (HC) ( n = 22) (Fig
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts
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The observation in this study in hepatocytes that protein-SSG formation by either GSSG accumulation or treatment with a direct S -glutathionylation induction agent resulted in IKK--SSG formation, leading to its suppression, was supported by a previous study reporting that S -glutathionylation was associated with suppressed IKK- activity in epithelial cells 41
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