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Figure 3 Citrullination of arginine residues in myelin basic protein (MBP)and likely other CNS proteins as wellseems to be one important post-translational modification associated with inflammatory demyelination
Elevated fasting insulin levels, as observed in this case, suggest an imminent risk of developing type 2 diabetes during childhood, in addition to predisposition to dyslipidemia, hepatic steatosis, and metabolic syndrome
Like other transmembrane proteins, SLC7A11 protein is synthesized in endoplasmic reticulum (ER) and subsequently transferred to the Golgi apparatus by vesicular and ultimately functions on the cell membrane [20]
The result is targeted mobilization of the most dangerous fat compartment
Understanding the common and unique roles among the members of the hub will be crucial to understanding how the hub is buffered to maintain stem cells under a variety of physiological and environmental conditions
