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Further Nrf2 translocates into the nucleus, heterodimerizes with one of the small musculo-aponeurotic fibrosarcoma (sMaf) proteins, binds to the antioxidant responsive element (ARE) or electrophile responsive element (EpRE) and promotes the transcription of genes encoding defense proteins/enzymes (Yamamoto et al., 2018)
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In conclusion, B12 injections are a safe and effective way to improve overall health and well-being
Others benefit from ongoing maintenance therapy
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