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The most common adverse events with CagriSema were gastrointestinal, and the vast majority were mild to moderate and diminished over time, consistent with the GLP-1 receptor agonist class

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healthcare professionals should review concomitant diabetes medicines before and during treatment Delayed gastric emptying as with other GLP-1-based therapies, retatrutide may slow gastric emptying, which could affect the absorption of some oral medicines

Peptide-specific water recommendations While the formula works universally, certain peptides have specific considerations that affect the optimal water volume