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2001 (animal lipolysis data, no pediatric data) Monitoring requirement / Height velocity, Tanner staging, fasting glucose, and IGF-1 every 3 months minimum FDA pediatric weight-management approvals / Orlistat (age 12+), liraglutide 3 mg (age 12+), semaglutide 2.4 mg (age 12+) Mental health screen / Mandatory at baseline and every visit per AAP obesity guidelines What Is AOD-9604 and Why Is It Being Asked About in Adolescents
doi: 10.1016/j.tins.2008.06.006, 28
However, this does not rule out B12 supplementation
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However, conducting a meta-analysis across studies remains challenging due to heterogeneity in disease characteristics, clinical outcomes, and evaluation metrics
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