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Step 5: Address Sleep and Stress If youre sleeping fewer than seven hours a night consistently, your hormonal environment is actively working against fat loss

GLP-1 medications can be especially relevant in these cases because they affect appetite and glucose-related pathways

Novos high-dose oral Wegovy, tested in the OASIS 1 trial, delivered even more dramatic results: patients taking 50 mg daily lost an average of 15.1% of their body weight over 68 weeks, with nearly 85% losing at least 5%

In lab and animal work, KPV has shown anti-inflammatory effects in the gut

The reason for this is clear: a large body of clinical evidence shows the drugs can help patients lose 15% to 25% additional weight when used alongside evidence-based lifestyle interventions (counseling, diet, and exercise)