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Safety, tolerability and pharmacokinetics of PL 14736, a novel agent for treatment of ulcerative colitis, in healthy male volunteers

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In this study, we first apply this experimental reverse engineering approach to compare the redox properties of pheomelanin and eumelanin using model synthetic pigments prepared by oxidation of the biosynthetic precursors under physiologically relevant conditions

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It was also observed that group A-infected cells released significantly higher levels of proinflammatory cytokines and nitric oxide (NO) as compared to group B-infected or noninfected cells