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Presented for research literature review only Li C et al
GSH/GSSG levels were measured and LPS-stimulated ROS production was quantified by electron paramagnetic resonance (EPR)
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Additionally, under the pro-inflammatory conditions -cells begin to express MHC-II, which enables them to present autoantigens (notably insulin neoantigens) to antigen presenting cells ( Similarly, under T2D conditions the crosstalk between macrophages and -cells plays a major initiating role in establishing -cell dysfunction, and a pro-inflammatory macrophage phenotype
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