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The rationale is that AOD 9604 preferentially targets adipose tissue, which might help shift the composition of weight loss more toward fat and away from lean mass

Subsequent interest in AOD-9604 has been limited to niche research areas, particularly osteoarthritis, where intra-articular injection might bypass systemic bioavailability limitations

Research applications focus on body composition optimization, energy expenditure, and metabolic health protocols particularly around visceral fat reduction and metabolic efficiency

Additionally, the absorption process itself is competitive, with amino acids and other nutrients vying for uptake in the small intestine

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