On the molecular level, human microRNAs (miRNA) have also been identified as potential early biomarkers for indicating APAP-induced hepatotoxicity at a stage before alanine aminotransferases become elevated
They may not last long, but they deliver high current
While longitudinal assessment across the postnatal period will be essential to determine persistence and developmental consequences, co-exposure to stress and THC at this early timepoint was associated with marked disruptions in maternal regulation, including reduced litter size, increased pup mortality, and delayed pup retrieval
Similarly, postmortem studies face challenges in reliably documenting the history of inflammation, infections, or other chronic medical conditions
doi: 10.2337/dbi21-0004 64 FriasJPDaviesMJRosenstockJPerez ManghiFCFernandez LandoLBergmanBKet al