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Protection is likely mediated by redox activation of the AMPK and NRF2 pathways
doi: 10.1016/j.cmet.2019.09.016 Summary Keywords type 2 diabetes mellitus, cardiovascular disease, acylcarnitine, metabolism, relationship Citation Zhao S, Liu M-L, Huang B, Zhao F-R, Li Y, Cui X-T and Lin R (2021) Acetylcarnitine Is Associated With Cardiovascular Disease Risk in Type 2 Diabetes Mellitus
Notably, the accumulation of PUFA oxides stands as a hallmark of ferroptosis, which represents a distinct form of cell death (Ye et al., 2020)
Cysteine starvation activates the redox-dependent mitochondrial permeability transition in retinal pigment epithelial cells
Panels A, B, and C show the percentage of surviving hepatocytes for females (blue curves) and males (red curves) for a 15 g dose, an 18 g dose of APAP, and a 30 g dose of APAP, respectively, over the first 80 h after ingestion
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