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Physiological review
Experimental DPN in rat models have identified early metabolic abnormalities with consequences for nerve conduction velocities and endoneurial blood flow
Standard dosages range from 0.25 mg to 2.4 mg for weekly injections, depending on the prescription
In practice this means an unbuffered aqueous preparation can look cloudy at a concentration that dissolves cleanly in a mildly alkaline buffer, and that clarity on its own is not a purity result
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