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Clinical trials (the STEP programme) demonstrated average weight loss of approximately 15% of body weight over 68 weeks
TB-500 has a distinct amino acid segment [(17)LKKTETQ(23)] which is hypothesized to be responsible for actin binding and potentially enhancing cellular motility
Studies by Malinda et al
Studies like the STEP 4 and SURMOUNT-4 trials have shown that if you stop taking the medication, you are likely to regain a significant portion of the lost weight
However, its gastrointestinal side effectsparticularly nausea, vomiting, and diarrheacan lead to dehydration, a well-established risk factor for nephrolithiasis
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