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Instead, its activity is believed to be mediated via adipocyte-specific signaling cascades, which gives the fragment a uniquely narrow pharmacological footprint for a peptide of its molecular size and makes it attractive to investigators who want clean lipolytic readouts

Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders

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Uses Maintenance treatment of pernicious anemia Vitamin B12 deficiency due to poor absorption Vitamin B12 deficiency in strict vegetarians Deficiency caused by stomach or intestinal disorders Vitamin B12 deficiency after certain stomach surgeries Contraindications If you are allergic to cyanocobalamin or any other ingredient of Naso B12 nasal spray If you have had a severe reaction to cobalt or vitamin B12 If you have early Lebers disease (a hereditary eye condition) Side effects Headache Nausea Runny nose (rhinitis) Dizziness Mild nasal irritation Precautions and Warnings Pregnancy Breast Feeding Driving Alcohol Other General Warnings You have kidney disease, have had a kidney transplant, or have liver disease You are allergic to any component of Naso B12 nasal spray You are taking other medicines or supplements You have nasal congestion, allergic rhinitis, or a cold You have anemia not yet been properly diagnosed You have early Lebers disease You have low potassium levels Directions for Use Use Naso B12 nasal spray exactly as prescribed by your doctor