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NAD+: Essential for energy production, DNA repair, and anti-aging
However, KYNA influences AMPAR activity predominantly through indirect mechanisms, namely its non-competitive allosteric inhibition of presynaptic 7nAChRs on glutamatergic terminals in mood-related circuits, leading to reduced glutamate release and downstream modulation of excitatory signalling [29, 30]
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10.3389/fphys.2022.803445 28 HuQ.ZhangL.TaoY.XieS.WangA.LuoC.et al (2024)
Theyre very simple molecules. The compounds themselves are an active area of clinical research, studied for their role in tissue repair and age-related decline
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