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These effects are seen even outside of diabetes control.[ref] Decreased colon cancer mortality: A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)
87 Thus, high GSH may reduce the mutation rate in genes encoding drug targets such as ribosomal proteins or DNA gyrase
In addition, it is one of a few antihyperglycemic agents associated with improvements in cardiovascular morbidity and mortality, which is a major cause of death in patients with type 2 diabetes
Are pregnant or breastfeeding (safety data are limited
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