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Platelet HMGB1 is required for efficient bacterial clearance in intra-abdominal bacterial sepsis in mice
Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes
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Furthermore, when the delivery rate of NEFAs inside hepatocytes exceeds the rate of intracellular -oxidation and/or formation to neutral TG, excess NEFAs can enter into harmful non-oxidative pathways
When initiating or escalating tirzepatide, doses of insulin or sulfonylureas should be reduced to minimize hypoglycemia risk
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