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This is modest because the starting dose is low
In Phase 2 trials, retatrutide showed an average weight loss of 24.2% at 48 weeks, and recent Phase 3 data showed up to 28.7% weight loss at 68 weeks with the 12 mg dose
This timing schedule optimizes absorption while keeping the routine simple enough to maintain consistently
Others move through the escalation steadily
This suggests a dose-response
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