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For the [U 13 C]glutamine isotopic tracing analyses (Fig 2E), MYC liver tumors were generated through hydrodynamic transfection of 8weekold FVB/n male mice (Taconic Biosciences) (Fig EV3), as described previously 28
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193 In addition, the relative contribution of these pathways and enzymes to NADPH production can be variable in different cell types and under different conditions
Mattson MP, Gleichmann M, Cheng A
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