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Current GLP-1 therapies have transformed obesity care, but challenges around GI side effects, lengthy titration schedules, adherence, and patient persistence remain significant barriers for many patients

These medications work by mimicking the hormone GLP-1, which helps regulate appetite and food intake, making them beneficial for weight management

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Nutrient competition problems High-dose multivitamins often contain nutrients that block each others absorption

while these effects were rescued by knockdown of p53 with p53 siRNA or knockdown of progerin with progerin siRNA, except knockdown of p21