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High-dose therapy may also cause a brief increase in blood pressure, though this usually returns to baseline within a few hours

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Lindsay Allen said that smaller, repeated doses of B12 during breastfeeding, rather than a single one-a-day supplement, appear to be more effective for the mothers B12 status (NASEM, 2020)

However, other studies haven't seen a link between low levels of B12 and cognitive problems or an improvement in these symptoms after getting extra doses of B12