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Site-directed mutagenesis and inhibition assays revealed that Phe-9 is potentially an important residue for the binding of the inhibitor S-hexyl glutathione (GTX) [77]
About 75% had gastrointestinal side effects, but few discontinued treatment
Use during pregnancy or breastfeeding is not recommended due to insufficient study
doi:10.1016/j.ejps.2005.12.007 Kohalmy K, Vrzal R
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