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September 36, 2025
GLP-1 has the highest substrate specificity for DPP-4, but DPP-4 has additional substrates and inhibition therefore extends the biological half-life of the incretin hormone GIP, brain natriuretic peptide, and many others (10, 19)
Int J Poult Sci
TMAO increases trans-differentiation of human primary renal fibroblasts into myofibroblasts in conjunction with TGF-1 signaling Based on TMAOs detrimental association with kidney damage of diverse aetiologies 19,20 similar to renal fibrosis 46 , we investigated the impact of TMAO on human primary renal fibroblasts (HRFs)
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