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And these cytokines will shut off the brain's ability to make all the triggering hormones, to make testosterone, estrogen, progesterone, allopregnenolone, pregnenolone," Gordon said, underscoring the importance of managing inflammation and hormonal balance

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GLP-1 and GIP are gut-derived incretin hormones that augment glucose-stimulated insulin secretion and have been shown to have important roles in weight regulation

But she adds that she tries to be fat-positive and hopes others feel empowered to make their own decisions about their body size, especially when weight stigma remains an issue in society as well as in the medical community