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c-Met: structure, functions and potential for therapeutic inhibition
Liao et al
Composed of three amino acidscysteine, glycine, and glutamic acidit plays a crucial role in protecting cells from oxidative stress, detoxifying the body, and supporting the immune system
Another factor to consider is long-term benefits with weight-loss or possible disease improvement would require continued use of GLP-1 agonist in addition to other IBD treatment options, which can be an additional financial or emotional burden on patients that would need further exploring as well.
Phase 2 trials showed 17.5% weight loss at 24 weeks and 24.2% at 48 weeks at the 12mg dose
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