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The extension gave industry groups more time to respond
Semaglutide: Primarily approved for type 2 diabetes and weight management, it works by increasing insulin secretion and reducing appetite
Sermorelin If you are currently using sermorelin or other hormone-related therapies, your provider should review them before determining whether PT-141 is appropriate
These effects were consistent across participants aged 65 and 60 years with obesity or overweight and at least one weight-related comorbidity experienced a 510% reduction in baseline body weight following 24 weeks of liraglutide treatment, although body composition was not assessed in this study [44]
In the Phase 2 retatrutide trial, some groups used a lower starting dose (2 mg vs 4 mg) and the study notes side effects were "partially mitigated" with a lower starting dose
