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The peak HR increase mirrored the PK profile, which shows that the maximum plasma concentration of exenatide is reached 2 h after injection [20]
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However, there was no change in nerve conduction or sensory function
As a synthetic analog of growth hormone-releasing hormone (GHRH), sermorelin therapy works by encouraging the pituitary gland to release more of the naturally occurring growth hormone that declines with age
For instance, the early suppression of C-X-C motif chemokine 12 (Cxcl12) may prevent peripheral leukocyte influx into the brain, reducing inflammation and promoting functional recovery
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