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No ACTH, cortisol, or prolactin elevation at therapeutic doses (key selectivity advantage over GHRP-2/GHRP-6)
This rapid clearance profile is essential for procurement in studies requiring physiological, pulsatile receptor activation rather than continuous baseline elevation, ensuring long-term assay reproducibility
Anal Biochem 74:214226 Jaworek J, Leja-Szpak A, Bonior J, Nawrot K, Tomaszewska R, Stachura J, Sendur R, Pawlik W, Brzozowski T, Konturek SJ (2003) Protective effect of melatonin and its precursor L-tryptophan on acute pancreatitis induced by caerulein overstimulation or ischemia/reperfusion
doi: 10.1038/s41580-021-00418-x 125 JainS
Stimulus-Secretion Coupling in Pancreatic Beta-Cells
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