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Continuously injecting into the same spot can lead to lipohypertrophy, a buildup of fatty tissue that can hinder absorption, or lipoatrophy, a loss of fat that can cause dents in the skin
The pivotal Phase 2 trial (NCT04881760), published in The New England Journal of Medicine (Jastreboff et al., 2023), enrolled 338 adults with BMI 30 or higher
Formulation and Delivery Format 22% The products delivery format accounted for 22% of the score
We answer these questions before anything gets prescribed: We build a strategy around the individual, the goal, the full clinical picture, and whether the approach is effective
One key difference: tirzepatide is a dual GIP/GLP-1 receptor agonist, while semaglutide targets only GLP-1
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