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Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome
There may be swelling, redness, or bruising from the injections, but these usually subside over time
Weedon, Cadmon K
Intriguingly, MRI evidence of BBB disruption has been noted in seemingly normal white matter even before the emergence of enhancing lesions, as well as in non-enhancing regions, implying that BBB impairment precedes both clinical symptoms and other MRI-evident changes in the disease course
Kumar R, Chaudhary AK, Woytash J, Inigo JR, Gokhale AA, Bshara W, et al
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