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Conclusions Evidence accrued so far suggest that GLP-1RA could exert a modest renal benefit alongside CV protection, justifying its place as second-line drug in patients with T2D and CKD not achieving glycemic control with SGLT-2i and metformin according to KDIGO guidelines [87]
Early studies suggest that patients can achieve similar or even superior weight loss outcomes compared to GLP-1 monotherapy, with noticeable results within a few weeks to months
With careful management and a proactive approach, GLP-1 agonists can be a powerful tool in achieving your health goals
Always start at the lower end of each compound's dosing range
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