However, developers of GLP-2 therapies for chronic IBD will need to address prescriber concerns regarding long-term trophic effects and the necessity for mucosal dysplasia surveillance
Mota Martins L, Soares de Oliveira AR, Clmaco Cruz KJ, Borges de Arajo CG, de Oliveira FE, Santos de Sousa G, et al
Published research on glucagon-mediated energy expenditure shows that the thermogenic effect comes primarily from fat oxidation rather than protein catabolism, suggesting that the additional weight loss driven by glucagon receptor activation may be disproportionately fat mass
For one, it may support weight management by regulating appetite, so people can manage their calorie intake more effectively
Most common side effects tend to resolve within the first several weeks of treatment as the body adjusts