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Glucagon-like peptide-1 (GLP-1) is a hormone naturally produced in your gut in response to food, especially carbohydrates and sugars

Furthermore, phenformin could also display synergism with other anti-cancer molecules (i.e., immune-therapeutics, chemotherapeutic)

Ethics declarations Competing interests MRH receives funding from Zealand Pharma and Novo Nordisk that was not used in support of these studies

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The emergence of pharmacotherapies targeting these non-anatomical mechanisms, alongside continued refinement of phenotyping tools, offers hope that personalized treatment will soon extend well beyond weight management alone. Even in patients with obesity, GLP-1s can help unmask other drivers of OSA