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Safety evaluation Given that psoriasis is a chronic autoimmune disease requiring long-term topical medication, we evaluated the in vivo safety of OA-NPs@OA by applying them topically to healthy mice twice daily for 7 consecutive days
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Not FDA-approved for any therapeutic use
Consequently, simulations suggest that while doxorubicin redox metabolism impacts GSH metabolism, the concentrations required to illicit a toxic response, with either a single or extended exposure, reside outside that of the therapeutic dosing range
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