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A previous meta-analysis of NAC use in COPD found that it reduced the occurrence of exacerbations by roughly half over the treatment period, an effect somewhat attenuated by simultaneous steroid use, but not active smoking.Men with idiopathic infertility given 600mg per day had improvement in several semen parameters as well as plasma antioxidant status

It is especially common for drugs that require multiple doses drawn from the same vial

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L-carnitine Supplemented Extender Improves Cryopreserved-thawed Cat Epididymal Sperm [PMID: 25050016] Laboratory literature summary: L-carnitine Supplemented Extender Improves Cryopreserved-thawed Cat Epididymal Sperm Motility