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reported that the ability of islet conditioned media to increase cAMP levels was maintained when a high-affinity glucagon antibody was added to the conditioned media, implying that islet-derived GLP-1, rather than glucagon, was the primary active ligand for the GLP-1R in this model
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What Made GLP-1 Manufacturing So Hard GLP-1 receptor agonists are complex synthetic peptides
343 , d5928 (2011)
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