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Retatrutide TRIUMPH-2/3: 22.6% Loss in Diabetes & CVD Lilly's retatrutide met endpoints in two new Phase 3 trials up to 22.6% weight loss in obesity with diabetes and heart disease
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The myotendinous junction, where muscle and tendon meet, also responds positively to BPC-157 treatment
A 2015 study by Huang and colleagues in Drug Design, Development and Therapy used a rat alkali-burn model (n=10 per group) and HUVECs treated with BPC-157 at 200800 ng/mL, reporting accelerated wound closure with enhanced granulation tissue, reepithelialization, and dermal remodeling by day 18, alongside increased endothelial migration and vascular tube formation in vitro via ERK1/2 phosphorylation though the abstract does not report numeric % wound closure or p-values
This lack of delay would represent a major advantage if translatable to humans, given that conventional antidepressants typically require 2-6 weeks before patients experience relief
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