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In lab and clinical research, its been observed to activate fibroblasts (the cells that produce collagen), increase glycosaminoglycan synthesis (which helps skin retain water), modulate matrix metalloproteinases (MMPs, the enzymes that break down old tissue), and act as a copper cofactor in antioxidant pathways
Ge X, Lu J, Yu C, Guo W, Tian T, Xu X, et al
This keeps B12 levels up
Research has shown that MK-677 increases the secretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), but does not affect cortisol levels
Diabetes Metab Syndr (2019) 13(2):164956
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