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confirmed that in MCF-7 cells, which a low aggressive breast cancer cell line, the expression of GPx2 can be substantially up-regulated by retinoic acid [94]

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200 A randomized placebo-controlled trial involving 75 subjects with fibromyalgia found 100 mg of oral magnesium (as magnesium chloride) once daily for one month improved scores on the Depression Anxiety Stress Scale and reduced pain severity in a subgroup of participants with mild-to-moderate stress, but had no effect on symptom parameters in those with severe-to-extremely severe stress

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