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These symptoms may lead to reduced oral intake and dehydration, further compromising intravascular volume and blood pressure stability

GLP-1s may play a protective role in addressing these risks

Certain agents (liraglutide, injectable semaglutide, dulaglutide) have demonstrated cardiovascular benefits in high-risk patients with type 2 diabetes

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Patients should also seek medical attention if headaches are accompanied by concerning symptoms, including: Visual disturbances such as blurred vision, double vision, or vision loss Neurological deficits including weakness, numbness, difficulty speaking, or coordination problems Altered mental status such as confusion, disorientation, or difficulty concentrating Severe nausea and vomiting that prevents adequate hydration or medication adherence Neck stiffness or photophobia (light sensitivity), which may suggest meningeal irritation High blood pressure readings, especially if 180/120 mmHg with headache Additionally, patients should consult their healthcare provider if headaches significantly interfere with daily activities or quality of life, or if over-the-counter analgesics provide insufficient relief