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Diabetes 67 (8), 15381548
Enhanced Insulin Sensitivity: Tirzepatide improves insulin secretion when blood sugar levels are high and reduces the livers production of glucose, helping to regulate blood sugar levels effectively
On tolerability, retatrutide's GI adverse event rate is higher than tirzepatide's at matched mechanistic dose, which is the tradeoff for the additional mechanism
10 The brain cannot process fatty acids, so they must be converted into ketone bodies first
During the last decade, reports have arisen of a metabolite produced by gut bacteria digesting L-carnitine (and choline) called TMA
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