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When GLP-1 is secreted from L-cells through the TGR5 agonist, it stimulates GLP-1R in enterochromaffin cells and induces serotonin or 5-hydroxytryptamine (5-HT) secretion from these cells
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It has been suggested that these alterations reflect an energy appeal reaction of the organism providing free energy in the circulation, which is needed by inflammatory cells (158)
This helps avoid any potential interactions and ensures both treatments work as intended
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