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Recommended B12 Dosing and Timing During GLP-1 Treatment For patients on semaglutide, typical B12 supplementation recommendations include intramuscular injections of 1,000 mcg monthly, sublingual lozenges at 1,000-2,000 mcg daily, or oral supplements at 2,000 mcg or higher daily
The results indicated a significant increased risk of cholelithiasis with the use of GLP-1 RAs when compared to placebo or active comparator
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Starting the medication at a low dose reduces early discontinuation and improves tolerability during dose escalation
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