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Carey and Pickarts ultrasound study found an average increase in collagen density of ~28% at 12 weeks, with top responders reaching 51%
(10) Apparently, the researchers observed collagen fibers that were more uniformly aligned along the ligament axis and more evenly spaced than in controls
The trial methodology may not always meet the gold-standard requirements of Western regulatory agencies, but the breadth and consistency of positive findings across multiple studies provides meaningful confidence in its efficacy and safety
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