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Anisimov VN, Khavinsov VKh, Alimova IN, Provintsiali M, Manchini R, Francheski K
Langmuir 27, 9551 (2011).CrossRefGoogle ScholarPubMed Irmukhametova, G.S., Fraser, B.J., Keddie, J.L., Mun, G.A., and Khutoryanskiy, V.V.: Hydrogen-bonding-driven self-assembly of PEGylated organosilica nanoparticles with poly(acrylic acid) in aqueous solutions and in layer-by-layer deposition at solid surface
Functional analyses in vitro showed low proliferation and enhanced migratory features in the carboplatin-resistance cells, compared to parental chemo nave cell line
FOXO4-DRI acts as a competitive inhibitor of this interaction binding directly to the transactivation domain 2 (TAD2) of p53, displacing FOXO4, and allowing phosphorylated p53 to be exported from the nucleus and directed to mitochondria, where it activates BAX, triggers caspase-3 cleavage (via the p53/BCL-2/Caspase-3 signalling pathway), and drives cell-intrinsic apoptosis
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