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From this period, two relevant studies using a larger amount of subjects clearly showed that patients with IBD have an altered intestinal barrier
When to Consult a Healthcare Provider You should consult with a healthcare provider before starting a GLP-1 such as semaglutide (Wegovy), tirzepatide (Zepbound), or any other medication, to make sure it's safe for you, especially if you have any underlying health conditions or are taking certain medications
Clinical trial dosing protocol Phase 2 and Phase 3 trials used a titration approach, starting at lower doses and increasing gradually to minimize gastrointestinal side effects
While these results were promising, Retatrutide remains under research evaluation and is not an FDA-approved medication
The same general principles apply to tirzepatide injections (Mounjaro, Zepbound), since they use the same subcutaneous delivery method
