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However, Novo Nordisk is expected to emerge as the leading company, having a large portfolio of GLP1 drugs, and is expected to capture 55 per cent of the market share in 2029.
Current clinical practice considerations emphasize the importance of ophthalmologic screening before initiating GLP-1 therapy in patients with longstanding diabetes and implementing more gradual titration schedules in those with known retinal disease to minimize the risk of early worsening
Koutkia, Polyxeni et al
The researchers found that people homozygous for the risk alleles at both the GLP1R and GIPR sites have a "14.8-fold increased odds" of experiencing moderate to severe vomiting on tirzepatide
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