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Description

These investigations focus on laboratory-based analysis of peptide identity verification, receptor-binding behaviorparticularly interactions with insulin-like growth factor (IGF-1) receptorsmolecular stability profiling, and signaling pathway activity under defined analytical conditions

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The topology of the conformational epitope indicates that binding of the nanobody prevents the conformational change to the postfusion form necessary for membrane fusion, which in turn would explain the neutralizing activity

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