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The main substrates for gut microbial metabolism include unprocessed or partially digested food elements and endogenous mucus produced by IECs
Seven binding proteins have been described (IGFBP-1 to -7)
The FOXO family is involved in regulating critical processes such as stress resistance, metabolism, cell cycle arrest, and apoptosis (Martins et al., 2016)
Heme produces signaling molecules, such as CO, biliverdin (BV), BR and Fe 2+ , through the catalysis of HO-1
Supplementary Video 9 (download MP4 Conformational changes at the NBSs of CydD and CydC when the lateral membrane gate closes, and conformational coupling to the NBDs
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