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An RCT in obese patients found that GLP-1 receptor activation by the agonist exenatide reduced brain responses on functional MRI to food cues in appetite- and reward-related brain areas including the insula and amygdala, correlating with reductions in food intake [18]
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10.1002/lary.20602 28 KnutsonJ
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What types of experimental models are commonly used with DSIP
Upregulated DGKH activates the mTOR signaling pathway by enhancing PA synthesis, thereby promoting HCC metastasis, stemness, and drug resistance [213]
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